History of Shiitake Mushroom History
The shiitake species( Lentinula edodes) translated from Japanese, " shii " refers to the tree on which these
mushrooms originally grew, while " také " simply means mushroom. These little beauties are venerated not
just because of their primordial origin, but because of the many health-boosting properties they contain
which discovered over centuries of ancient medicine.
It is also considered a medical mushroom in some forms of traditional medicine. Shiitake is regarded as a
good health-promoting fungus that's rich in protein and short of fat.As a plant,Lentinula edodes is believed
by nutritionists to possess some properties of the meat, therefore becomes popular all over world
Specifications of Shiitake Mushroom Extract from MAXINGREDA
Our Shiitake mushroom extract contain vitamins B1, B2, B12, and D, that increase energy levels, They have
strong anti-bacterial and anti-viral effects as well, Shiitake has been proven to treat patients with a wide
variety of illness including depression, common cold and flu, type 1 and type 2 diabetes, endometriosis
osteoporosis, stress, fatigue, and etc .For more information,please see below
Origin of Shiitake mushroom extract material -- Wild and Cultivated
They still grow wild, China yields around 80% of the world market in production,although Japan held this
distinction initially. Today, more than 200 growers in the U.S. utilize the labor-intensive but superior"forest
farming " method to produce shiitake mushrooms on hardwood logs. " Grow-at-home " kits prepared by
mushroom specialty companies also maintain a lively business.
For us used pure mycelium inoculation which get duanwood material like Fagaceae,betulaceae and hamame
-lidaceae hardwood as inoculation.
Compare wild shiitake little getting , we make duanwood pure mycelium inoculation for cultivation.And also
set up our own R & D cultivation techniques and then carry on the production. We are currently producing
large quantity shiitake which store loose shiitake mushrooms ( as well as maitake or reishi mushrooms ) is to
keep them in the refrigerator in a loosely closed paper bag after collecting material in the Sunday!
Our shiitake planted base is located in ZheJ iang province, different others with substitute materials
cultivation of edible fungi,ours shiitake are famous with rich nutritional like carbon source (Monosaccharides
disaccharides and polysaccharides ), mineral element ( Magnesium, sulfur, phosphorus, potassium, iron,zinc
manganese),Vitamins (like B2,B5,B6) and etc
Nutritional Profile of Shiitake Mushroom Extract Powder
Like most fungi,shiitake mushrooms offer a unique variety of phytonutrients,including their well-known beta
-glucan polysaccharides(especially lentinan and laminarin).A cholesterol-lowering nutrient called eritadenine
(or lentinacin)is found in shiitake,as well asthe recently discovered amino acid-like nutrient,ergothioneine
Shiitake mushrooms alsooffer a wide variety of conventional nutrients.They are an excellent source of copper
pantothenic acid,and selenium.They are a very good source of vitamin B2 and zinc.Additionally they are a
good source of manganese,vitamin B6,niacin,choline,dietary fiber,vitamin D,and folate.
Comparing the vitamins,minerals,antioxidants,and phytonutrients between foods,shiitake mushrooms are
completely unique.Copper figure most prominently,with 65%of the daily value per serving,significant because
copper is one of the few metallic elements accompanied by amino and fatty acids,essential to human health
Linoleic acid is one.Since the body can't synthesize copper,our diets must supply it regularly.But researchers
say that not only do few people eat adequate amounts of copper-containing foods,but copper deficiency can
also be a factor in coronary heart disease development.
Right behind copper's pantothenic acid and selenium,which provide 52%and 51%of the daily value,respective
Riboflavin,niacin,zinc,and manganese play supportive roles,along with
It is easy to take shortcuts when preparing mushroom extracts.The mushroom cell wall(chitin)is indigestible
to humans and requires expert preparation in order to be broken down so the medicinal compounds
Turkey Tail(Trametes versicolor),for example,has to be boiled for 62 hours to break down the cell wall and
make the medicinal compounds available.Shiitake requires alcohol extraction of the mycelium for some of
the most powerful compounds.That's why our Shiitake is only available as an alcohol extract,not capsules
Similar expertise is applied to all our medicinal mushroom products,to ensure their highest effectiveness.
Health Benefits of Shiitake Mushroom Extract Powder
Shiitake,maitake,and reishi mushrooms are widely referred to as"medicinal mushrooms"due to their long
history of medical use,particularly in oriental medicin e traditions.It's important to distinguish,however
between extracts and medicinal preparation made from these mushroom and their appearance as whole foods
in an everyday diet.Most of the medicinal research on shiitake mushrooms has been conducted on laboratory
animals or on individual cells studied in a laboratory setting.There are hundreds of lab and animal studies that
clearly document the medicinal properties of shiitake mushroom extracts.
That’s to say shiitake mushrooms:they can provide us with some fantastic health benefits.Below are areas of
health support that make the top of our list for shiitake mushrooms.
The famous immune-supportive components in shiitake mushrooms are its polysaccharides.(Polysaccharides
are large-sized carbohydrate molecules composed of many different sugars arranged in chains and branches.)
Although many fungi are wellknown for their polysaccharides,no single fungu has been more carefully studied
than the shiitake mushroom.
We know that this fungus is unique in its variety of polysaccharides,and especially its polysaccharide glucans.
(Glucan are polysaccharides in which all of the sugar components involve the simple sugar glucose)Among the
glucans contained in shiitake mushroom are alpha-1,6 glucan,alpha-1,4 glucan,beta-1,3 glucan,beta-1,6 glucan
1,4-D-glucans,1,6-D-glucans,glucan phosphate,laminarin,and lentinan.Shiitake mushrooms also contain some
important non-glucan polysaccharides,including fucoidans and galactomannins.The immune-related effects of
polysaccharides in shiitake mushrooms have been studied on laboratory animals under a wide variety of
circumstances,including exercise stress,exposure to inflammation-producing toxins,radiation exposure,and
The cardiovascular benefits of shiitake mushrooms have been documented in three basic areas of research
1)Cholesterol reduction.d-Eritadenine(also called lentinacin,or lentsine,and sometimes abbreviated as DEA)
is one of most unusual naturally occurring nutrients in shiitake mushrooms that has repeatedly been shown
to help lower total blood cholesterol.This nutrient is actually derived from adenine one of the building blocks
(nucleotides)in the mushroom's genetic material(DNA).The beta-glucans in shiitake mushrooms are also very
likely to contribute to its cholesterol-lowering impact.
2)Cardiovascular support involves the interaction between our cardiovascular system and our immune system
Recent studies have shown that shiitake mushrooms can help protect us against cardiovascular diseases
(including atherosclerosis)by preventing too much immune cell binding to the lining of our blood vessels.In
order for immune cells and other materials to bind onto our blood vessel linings,certain protein molecules
-called adhesion molecules must be produced and sent into action.By helping to block the adhesion molecule
production process,substances in shiitake mushrooms can help protect our blood vessels.(The adhesion
molecule production which is partially blocked by shiitake mushroom components includes the adhesion
molecules ICAM-1,VCAM-1,and E-selectin.)
3)Cardiovascular benefits involves antioxidant support.Chronic oxidative stress in our cardiovascular system
(ongoing,oxygenbased damage to our blood vessel linings)is a critical factor in the development of clogged
arteries(atherosclerosis)and other blood vessel problems.One of the best ways for us to reduce our risk of
chronic oxidative stress is consumption of a diet rich in antio-xidant nutrients.Shiitake mushrooms are a very
good source of three key antioxidant minerals:manganese,selenium,and zinc.They also contain some unusual
phytonutrient antioxidants.One of the best studied is ergothioneine(ET).This unique antioxidant is derived
from the amino acid histidine,although it's unusual since it contains a sulfur group of molecules that are not
present in histidine itself.In study on ET and our cells'oxidative stress levels,one fascinating finding has been
the special benefit of ET for cell components called mitochondria.Mitochondria use oxygen to produce energy
for the cell.Heart cells have greater concentrations of mitochondria than most any other cell type in the body
For this reason,researchers believe that ET may be one of the key nutrients from shiitake mushrooms that
provide us with cardiovascular support.
Most of the research on shiitake mushrooms and cancer has been conducted on laboratory animals or on
individual cells in laboratory setting and has involved mushroom extracts rather than whole mushrooms in food
form.For anti-cancer benefits especially with respect to prevention of prostate cancer,breast cancer,and colon
Medicinal extract from shiitake mushrooms have been studied much more extensively than the whole food itself.
In cell and laboratory animal experiments,numerous components of shiitake mushrooms have been show to help
block tumor growth sometimes by triggering programmed cell death(apoptosis)in the cancer cells.These
components have been collectively referred to as"anti-tumor mycochemicals"provided by shiitake mushrooms.
Researchers have speculated that more than100 different types of compounds in shiitake mushrooms may work
together to accomplish these anti-tumor results While the unique polysaccharides in shiitake mushrooms were
first thought to be its primary anti-cancer compounds,scientists are now convinced that shiitake provides many
non-polysaccharide substances that have anti-tumor effects.
The special combination of antioxidant found in shiitake mushroom together with their highly flexible support
for immune system function make them a natural candidate for providing us with protection from a variety of
problems involving oxidative stress and immune function.This includes rheumatoid arthritis(RA),an area that
has begun to interest shiitake mushroom researchers.
Medicinal extracts from shiitake mushrooms have well-documented effects on a variety of micro-organisms
including bacteria,fungi,and viruses(including human immunodeficiency virus-1,or HIV-1).
Preliminary Testing shows that A shiitake mushroom extract shows promise in curing HPV.
An early,pre-clinical trial has shown that Active Hexose Correlated Compound(AHCC),an extract from shiitake
mushrooms,can kill the human papillomavirus(HPV),the most common sexually transmitted infection in theU.S
A study by Dr.Judith A.Smith,Pharm.D.,an associate professor in the department of gynecologic oncology and
reproductive medicine at the University of Texas MD Anderson Cancer Center in Houston,also discovered that
AHCC lowered the rate of ovarian tumor growth.
Side Effects and Safety of Shiitake Extract
Most minor adverse effects are believed to be caused by lentinan,the polysaccharide derivative of shiitake
There has been one report each of depression,rigor,fever,chills,and abnormal blood cell counts;elevated liver
enzymes were reported in one study following treatment with lentinan in cancer patients.Shiitake can cause
abdominal discomfort and abnormal blood cell counts when taken by mouth.Abdominal obstruction and death
was reported due to the ingestion of a whole shiitake mushroom.Temporary diarrhea and abdominal bloating
may occur after taking high amounts of shiitake.Mushroom workers exposed to shiitake spores by inhalation
have experienced hypersensitivity pneumonitis.
Rapid IV infusion of lentinan,the polysaccharide derivative of shiitake,to advanced cancer patients reported
to cause anterior chese depression and dryness of the throat in one study;slow infusion relieved these
symptoms.Back pain and leg pain has been reported following the administration of lentinan in cancer patients.
Shiitake can cause"shiitake"dermatitis and possibly photosensitivity when taken by mouth.Allergic contact
dermatitis has been induced by shiitake hyphae.
Dosage of Shiitake Extract
Many shiitake supplements recommend a dosage of around 500 mg or 1500 mg.This is quite a variation so
what is the ideal dosage?It is thought that the ideal dosage is 1000 mg of shiitake extract per day to see
positive appetite-suppressing results.
Of course there are many variables that enter the equation.You body size,weight,health and metabolic rate
will all come into play.You may require more or even less than the 1000 mg.Most guideline on this recommend
that you start out at the lower limits say around 500mg and then judge the results for yourself.If you are happy
that your appetite is lowered then you might want to stick to this dosage.If you are not happy you may want to
increase the dosage.It should take a few days for you to see or feel the results so reserve judgment until then.
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